ITGA6 antibody (AA 870-1010)

Catalog No. ABIN6142566

This anti-ITGA6 antibody is a Rabbit Polyclonal antibody detecting ITGA6 in WB. Suitable for Human.

Quick Overview for ITGA6 antibody (AA 870-1010) (ABIN6142566)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITGA6 Antibody

Binding Specificity: AA 870-1010

Sequence: KVESKGLEKV TCEPQKEINS LNLTESHNSR KKREITEKQI DDNRKFSLFA ERKYQTLNCS VNVNCVNIRC PLRGLDSKAS LILRSRLWNS TFLEEYSKLN YLDILMRAFI DVTAAAENIR LPNAGTQVRV TVFPSKTVAQ Y

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 870-1010 of human Integrin alpha 6 (ITGA6/CD49f) (NP_001073286.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: ITGA6

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.,CD49f,ITGA6B,VLA-6,Integrin alpha 6,ITGA6,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Embryonic Stem Cells,Hematopoietic Progenitors,ITGA6

Molecular Weight: 106 kDa/119 kDa/121 kDa/122 kDa/124 kDa/126 kDa

Gene ID: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex