Integrin beta 3 antibody (AA 609-788)

Catalog No. ABIN6142583

This anti-Integrin beta 3 antibody is a Rabbit Polyclonal antibody detecting Integrin beta 3 in WB. Suitable for Human.

Quick Overview for Integrin beta 3 antibody (AA 609-788) (ABIN6142583)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin beta 3 Antibody

Binding Specificity: AA 609-788

Sequence: CGSCVCIQPG SYGDTCEKCP TCPDACTFKK ECVECKKFDR GALHDENTCN RYCRDEIESV KELKDTGKDA VNCTYKNEDD CVVRFQYYED SSGKSILYVV EEPECPKGPD ILVVLLSVMG AILLIGLAAL LIWKLLITIH DRKEFAKFEE ERARAKWDTA NNPLYKEATS TFTNITYRGT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 609-788 of human ITGB3 (NP_000203.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3

Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.,BDPLT16,BDPLT2,CD61,GP3A,GPIIIa,GT,Integrin beta 3,ITGB3,Cancer,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Cardiovascular,Angiogenesis,Blood,Cardiovascular diseases,Hypertension,ITGB3

Molecular Weight: 86 kDa/87 kDa

Gene ID: 3690

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex