JTB antibody (AA 31-105)

Catalog No. ABIN6142668

This anti-JTB antibody is a Rabbit Polyclonal antibody detecting JTB in WB. Suitable for Human.

Quick Overview for JTB antibody (AA 31-105) (ABIN6142668)

Target: JTB (Jumping Translocation Breakpoint (JTB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JTB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JTB Antibody

Binding Specificity: AA 31-105

Sequence: EAPVQEEKLS ASTSNLPCWL VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL MEQRL

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-105 of human JTB (NP_006685.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for JTB

Target: JTB (Jumping Translocation Breakpoint (JTB))

Alternative Name: JTB

Background: Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC, a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity.,JTB,HJTB,HSPC222,PAR,hJT,Cell Biology & Developmental Biology,JTB

Molecular Weight: 13 kDa/16 kDa

Gene ID: 10899

UniProt: O76095