KARS antibody (AA 298-597)

Catalog No. ABIN6142683

The Rabbit Polyclonal anti-KARS antibody has been validated for WB and IF. It is suitable to detect KARS in samples from Human.

Quick Overview for KARS antibody (AA 298-597) (ABIN6142683)

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KARS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KARS Antibody

Binding Specificity: AA 298-597

Sequence: IAPELYHKML VVGGIDRVYE IGRQFRNEGI DLTHNPEFTT CEFYMAYADY HDLMEITEKM VSGMVKHITG SYKVTYHPDG PEGQAYDVDF TPPFRRINMV EELEKALGMK LPETNLFETE ETRKILDDIC VAKAVECPPP RTTARLLDKL VGEFLEVTCI NPTFICDHPQ IMSPLAKWHR SKEGLTERFE LFVMKKEICN AYTELNDPMR QRQLFEEQAK AKAAGDDEAM FIDENFCTAL EYGLPPTAGW GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_005539.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Alternative Name: KARS

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,Epigenetics & Nuclear Signaling,KARS

Molecular Weight: 68 kDa/71 kDa

Gene ID: 3735

UniProt: Q15046