KLC1 antibody (AA 261-560)

Catalog No. ABIN6142903

This Rabbit Polyclonal antibody specifically detects KLC1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for KLC1 antibody (AA 261-560) (ABIN6142903)

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KLC1 Antibody

Binding Specificity: AA 261-560

Sequence: LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ NQGKYEEVEY YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG GWYKACKVDS PTVTTTLKNL GALYRRQGKF EAAETLEEAA MRSRKQGLDN VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE EVSMSVEWNG MRKMKLGLVN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 261-560 of human Kinesin light chain 1 (Kinesin light chain 1 (KLC1)) (NP_005543.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KLC1

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Alternative Name: KLC1

Background: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.,KLC1,KLC,KNS2,KNS2A,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Neuroscience,Cell Type Marker,Neuron marker,Axon marker,KLC1

Molecular Weight: 62-72 kDa

Gene ID: 3831

UniProt: Q07866

Pathways: Ribonucleoprotein Complex Subunit Organization