Cytokeratin 1 antibody (AA 200-450)

Catalog No. ABIN6143011

The Rabbit Polyclonal anti-Cytokeratin 1 antibody has been validated for WB. It is suitable to detect Cytokeratin 1 in samples from Human.

Quick Overview for Cytokeratin 1 antibody (AA 200-450) (ABIN6143011)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cytokeratin 1 Antibody

Binding Specificity: AA 200-450

Sequence: FLEQQNQVLQ TKWELLQQVD TSTRTHNLEP YFESFINNLR RRVDQLKSDQ SRLDSELKNM QDMVEDYRNK YEDEINKRTN AENEFVTIKK DVDGAYMTKV DLQAKLDNLQ QEIDFLTALY QAELSQMQTQ ISETNVILSM DNNRSLDLDS IIAEVKAQYE DIAQKSKAEA ESLYQSKYEE LQITAGRHGD SVRNSKIEIS ELNRVIQRLR SEIDNVKKQI SNLQQSISDA EQRGENALKD AKNKLNDLED A

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human Cytokeratin 1 (Cytokeratin 1 (KRT1)) (NP_006112.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: KRT1

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.,KRT1,CK1,EHK,EHK1,EPPK,K1,KRT1A,NEPPK,keratin 1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Microtubules,Extracellular Matrix,Cytokeratin,Keratin,Stem Cells,Cardiovascular,Angiogenesis,KRT1

Molecular Weight: 66 kDa

Gene ID: 3848

UniProt: P04264