L3MBTL2 antibody (AA 486-705)

Catalog No. ABIN6143059

This anti-L3MBTL2 antibody is a Rabbit Polyclonal antibody detecting L3MBTL2 in WB. Suitable for Human.

Quick Overview for L3MBTL2 antibody (AA 486-705) (ABIN6143059)

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L3MBTL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-L3MBTL2 Antibody

Binding Specificity: AA 486-705

Sequence: PATFCQKNDI ELTPPKGYEA QTFNWENYLE KTKSKAAPSR LFNMDCPNHG FKVGMKLEAV DLMEPRLICV ATVKRVVHRL LSIHFDGWDS EYDQWVDCES PDIYPVGWCE LTGYQLQPPV AAEPATPLKA KEATKKKKKQ FGKKRKRIPP TKTRPLRQGS KKPLLEDDPQ GARKISSEPV PGEIIAVRVK EEHLDVASPD KASSPELPVS VENIKQETDD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 486-705 of human L3MBTL2 (NP_113676.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Alternative Name: L3MBTL2

Background: Putative Polycomb group (PcG protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.,L3MBTL2,H-l(3)mbt-l,L3MBT,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,L3MBTL2

Molecular Weight: 69 kDa/79 kDa

Gene ID: 83746

UniProt: Q969R5