LAP3 antibody (AA 260-519)

Catalog No. ABIN6143087

The Rabbit Polyclonal anti-LAP3 antibody has been validated for WB. It is suitable to detect LAP3 in samples from Human.

Quick Overview for LAP3 antibody (AA 260-519) (ABIN6143087)

Target: LAP3 (Cytosol Aminopeptidase (LAP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LAP3 Antibody

Binding Specificity: AA 260-519

Sequence: VFLEIHYKGS PNANEPPLVF VGKGITFDSG GISIKASANM DLMRADMGGA ATICSAIVSA AKLNLPINII GLAPLCENMP SGKANKPGDV VRAKNGKTIQ VDNTDAEGRL ILADALCYAH TFNPKVILNA ATLTGAMDVA LGSGATGVFT NSSWLWNKLF EASIETGDRV WRMPLFEHYT RQVVDCQLAD VNNIGKYRSA GACTAAAFLK EFVTHPKWAH LDIAGVMTNK DEVPYLRKGM TGRPTRTLIE FLLRFSQDNA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LAP3

Target: LAP3 (Cytosol Aminopeptidase (LAP3))

Alternative Name: LAP3

Background: Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+ ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+, it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.,LAP3,HEL-S-106,LAP,LAPEP,PEPS,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Cardiovascular,Blood,Blood Pressure regulation,LAP3

Molecular Weight: 52 kDa/56 kDa

Gene ID: 51056

UniProt: P28838