LECT1 antibody (AA 75-334)

Catalog No. ABIN6143133

This anti-LECT1 antibody is a Rabbit Polyclonal antibody detecting LECT1 in WB and IF. Suitable for Human.

Quick Overview for LECT1 antibody (AA 75-334) (ABIN6143133)

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LECT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LECT1 Antibody

Binding Specificity: AA 75-334

Sequence: VHYTMSINGK LQDGSMEIDA GNNLETFKMG SGAEEAIAVN DFQNGITGIR FAGGEKCYIK AQVKARIPEV GAVTKQSISS KLEGKIMPVK YEENSLIWVA VDQPVKDNSF LSSKVLELCG DLPIFWLKPT YPKEIQRERR EVVRKIVPTT TKRPHSGPRS NPGAGRLNNE TRPSVQEDSQ AFNPDNPYHQ QEGESMTFDP RLDHEGICCI ECRRSYTHCQ KICEPLGGYY PWPYNYQGCR SACRVIMPCS WWVARILGMV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human LECT1 (NP_008946.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Alternative Name: LECT1

Background: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.,CNMD,BRICD3,CHM-I,CHM1,LECT1,MYETS1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,Cardiovascular,Angiogenesis,Angiogenic inhibitory factors,LECT1

Molecular Weight: 36 kDa/37 kDa

Gene ID: 11061

UniProt: O75829