LECT1 antibody (C-Term)

Catalog No. ABIN357871

This Rabbit Polyclonal antibody specifically detects LECT1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for LECT1 antibody (C-Term) (ABIN357871)

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LECT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-LECT1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects LECT1 (C-term). Predicted to Cross React with Mouse Rabbit (100 % Antigen Homology).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human LECT1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Alternative Name: Chondromodulin-1

Background: LECT1 a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.Synonyms: CHMI, ChM-I, Chondromodulin-I, Chondromodulin1, LECT1, Leukocyte cell-derived chemotaxin 1

Molecular Weight: 37102 Da

Gene ID: 11061, 9606

UniProt: O75829