LRAT antibody (AA 1-194)

Catalog No. ABIN6143312

The Rabbit Polyclonal anti-LRAT antibody (ABIN6143312) specifically detects LRAT in WB and IF. The antibody is reactive with Human samples.

Quick Overview for LRAT antibody (AA 1-194) (ABIN6143312)

Target: LRAT (Lecithin Retinol Acyltransferase (Phosphatidylcholine--Retinol O-Acyltransferase) (LRAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRAT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LRAT Antibody

Binding Specificity: AA 1-194

Sequence: MKNPMLEVVS LLLEKLLLIS NFTLFSSGAA GEDKGRNSFY ETSSFHRGDV LEVPRTHLTH YGIYLGDNRV AHMMPDILLA LTDDMGRTQK VVSNKRLILG VIVKVASIRV DTVEDFAYGA NILVNHLDES LQKKALLNEE VARRAEKLLG FTPYSLLWNN CEHFVTYCRY GTPISPQSDK FCETVKIIIR DQRS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human LRAT (NP_004735.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LRAT

Target: LRAT (Lecithin Retinol Acyltransferase (Phosphatidylcholine--Retinol O-Acyltransferase) (LRAT))

Alternative Name: LRAT

Background: The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.,LRAT,LCA14,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,LRAT

Molecular Weight: 25 kDa

Gene ID: 9227

UniProt: O95237