LY6E antibody (AA 21-101)

Catalog No. ABIN6143391

This Rabbit Polyclonal antibody specifically detects LY6E in WB and IF. It exhibits reactivity toward Human.

Quick Overview for LY6E antibody (AA 21-101) (ABIN6143391)

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LY6E antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LY6E Antibody

Binding Specificity: AA 21-101

Sequence: LMCFSCLNQK SNLYCLKPTI CSDQDNYCVT VSASAGIGNL VTFGHSLSKT CSPACPIPEG VNVGVASMGI SCCQSFLCNF S

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LY6E

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Alternative Name: LY6E

Background: GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity. Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA. Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs activity (By similarity.,LY6E,RIG-E,RIGE,SCA-2,SCA2,TSA-1,LY6E

Molecular Weight: 13 kDa

Gene ID: 4061

UniProt: Q16553

Pathways: Hormone Transport