MafF antibody (AA 75-164)

Catalog No. ABIN6143431

The Rabbit Polyclonal anti-MafF antibody has been validated for WB. It is suitable to detect MafF in samples from Human.

Quick Overview for MafF antibody (AA 75-164) (ABIN6143431)

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MafF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MafF Antibody

Binding Specificity: AA 75-164

Sequence: QKEELQKQKS ELEREVDKLA RENAAMRLEL DALRGKCEAL QGFARSVAAA RGPATLVAPA SVITIVKSTP GSGSGPAHGP DPAHGPASCS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 75-164 of human MAFF (NP_036455.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Alternative Name: MAFF

Background: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.,MAFF,U-MAF,hMafF,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Endocrine & Metabolism,MAFF

Molecular Weight: 14 kDa/17 kDa

Gene ID: 23764

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction