MATK antibody (AA 352-466)

Catalog No. ABIN6143578

This Rabbit Polyclonal antibody specifically detects MATK in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for MATK antibody (AA 352-466) (ABIN6143578)

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MATK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MATK Antibody

Binding Specificity: AA 352-466

Sequence: PEALKHGKFT SKSDVWSFGV LLWEVFSYGR APYPKMSLKE VSEAVEKGYR MEPPEGCPGP VHVLMSSCWE AEPARRPPFR KLAEKLAREL RSAGAPASVS GQDADGSTSP RSQEP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Alternative Name: MATK

Background: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.,MATK,CHK,CTK,HHYLTK,HYL,HYLTK,Lsk,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,MATK

Molecular Weight: 51 kDa/56 kDa

Gene ID: 4145

UniProt: P42679