MTHFD2 antibody (AA 40-250)

Catalog No. ABIN6144144

This Rabbit Polyclonal antibody specifically detects MTHFD2 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for MTHFD2 antibody (AA 40-250) (ABIN6144144)

Target: MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTHFD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MTHFD2 Antibody

Binding Specificity: AA 40-250

Sequence: ISGRKLAQQI KQEVRQEVEE WVASGNKRPH LSVILVGENP ASHSYVLNKT RAAAVVGINS ETIMKPASIS EEELLNLINK LNNDDNVDGL LVQLPLPEHI DERRICNAVS PDKDVDGFHV INVGRMCLDQ YSMLPATPWG VWEIIKRTGI PTLGKNVVVA GRSKNVGMPI AMLLHTDGAH ERPGGDATVT ISHRYTPKEQ LKKHTILADI V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTHFD2

Target: MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))

Alternative Name: MTHFD2

Background: This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.,MTHFD2,NMDMC,MTHFD2

Molecular Weight: 26 kDa/37 kDa

Gene ID: 10797

UniProt: P13995