MTHFD2 antibody (AA 40-250)
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- Target See all MTHFD2 Antibodies
- MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
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Binding Specificity
- AA 40-250
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MTHFD2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- ISGRKLAQQI KQEVRQEVEE WVASGNKRPH LSVILVGENP ASHSYVLNKT RAAAVVGINS ETIMKPASIS EEELLNLINK LNNDDNVDGL LVQLPLPEHI DERRICNAVS PDKDVDGFHV INVGRMCLDQ YSMLPATPWG VWEIIKRTGI PTLGKNVVVA GRSKNVGMPI AMLLHTDGAH ERPGGDATVT ISHRYTPKEQ LKKHTILADI V
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2).
- Isotype
- IgG
- Top Product
- Discover our top product MTHFD2 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))
- Alternative Name
- MTHFD2 (MTHFD2 Products)
- Synonyms
- nmdmc antibody, AW558851 antibody, NMDMC antibody, wu:fb38b11 antibody, wu:fe12e11 antibody, zgc:91891 antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase L homeolog antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase antibody, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like S homeolog antibody, methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase antibody, mthfd2.L antibody, MTHFD2 antibody, mthfd2 antibody, mthfd2l.S antibody, Mthfd2 antibody
- Background
- This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.,MTHFD2,NMDMC,MTHFD2
- Molecular Weight
- 26 kDa/37 kDa
- Gene ID
- 10797
- UniProt
- P13995
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