MVK antibody (AA 40-300)

Catalog No. ABIN6144204

This Rabbit Polyclonal antibody specifically detects MVK in WB. It exhibits reactivity toward Human.

Quick Overview for MVK antibody (AA 40-300) (ABIN6144204)

Target: MVK (Mevalonate Kinase (MVK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MVK Antibody

Binding Specificity: AA 40-300

Sequence: RLQPHSNGKV DLSLPNIGIK RAWDVARLQS LDTSFLEQGD VTTPTSEQVE KLKEVAGLPD DCAVTERLAV LAFLYLYLSI CRKQRALPSL DIVVWSELPP GAGLGSSAAY SVCLAAALLT VCEEIPNPLK DGDCVNRWTK EDLELINKWA FQGERMIHGN PSGVDNAVST WGGALRYHQG KISSLKRSPA LQILLTNTKV PRNTRALVAG VRNRLLKFPE IVAPLLTSID AISLECERVL GEMGEAPAPE QYLVLEELID M

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human MVK (NP_000422.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MVK

Target: MVK (Mevalonate Kinase (MVK))

Alternative Name: MVK

Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.,MVK,LRBP,MK,MVLK,POROK3,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,MVK

Molecular Weight: 42 kDa

Gene ID: 4598

UniProt: Q03426