MXI1 antibody (AA 170-295)

Catalog No. ABIN6144206

The Rabbit Polyclonal anti-MXI1 antibody has been validated for WB. It is suitable to detect MXI1 in samples from Human.

Quick Overview for MXI1 antibody (AA 170-295) (ABIN6144206)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXI1 Antibody

Binding Specificity: AA 170-295

Sequence: HTTLGLLNKA KAHIKKLEEA ERKSQHQLEN LEREQRFLKW RLEQLQGPQE MERIRMDSIG STISSDRSDS EREEIEVDVE STEFSHGEVD NISTTSISDI DDHSSLPSIG SDEGYSSASV KLSFTS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-295 of human MXI1 (NP_569157.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Alternative Name: MXI1

Background: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1,MAD2,MXD2,MXI,bHLHc11,Epigenetics & Nuclear Signaling,Transcription Factors,MXI1

Molecular Weight: 20 kDa/21 kDa/26 kDa/32 kDa

Gene ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location