NAGS antibody (AA 295-534)

Catalog No. ABIN6144346

The Rabbit Polyclonal anti-NAGS antibody has been validated for WB. It is suitable to detect NAGS in samples from Human.

Quick Overview for NAGS antibody (AA 295-534) (ABIN6144346)

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAGS Antibody

Binding Specificity: AA 295-534

Sequence: NTGGLRDSSH KVLSNVNLPA DLDLVCNAEW VSTKERQQMR LIVDVLSRLP HHSSAVITAA STLLTELFSN KGSGTLFKNA ERMLRVRSLD KLDQGRLVDL VNASFGKKLR DDYLASLRPR LHSIYVSEGY NAAAILTMEP VLGGTPYLDK FVVSSSRQGQ GSGQMLWECL RRDLQTLFWR SRVTNPINPW YFKHSDGSFS NKQWIFFWFG LADIRDSYEL VNHAKGLPDS FHKPASDPGS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 295-534 of human NAGS (NP_694551.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NAGS

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Alternative Name: NAGS

Background: The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.,NAGS,AGAS,ARGA,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,NAGS

Molecular Weight: 58 kDa

Gene ID: 162417

UniProt: Q8N159