NDC80 antibody (AA 343-642)

Catalog No. ABIN6144439

This Rabbit Polyclonal antibody specifically detects NDC80 in WB. It exhibits reactivity toward Human.

Quick Overview for NDC80 antibody (AA 343-642) (ABIN6144439)

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDC80 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDC80 Antibody

Binding Specificity: AA 343-642

Sequence: ETIKQENTRL QNIIDNQKYS VADIERINHE RNELQQTINK LTKDLEAEQQ KLWNEELKYA RGKEAIETQL AEYHKLARKL KLIPKGAENS KGYDFEIKFN PEAGANCLVK YRAQVYVPLK ELLNETEEEI NKALNKKMGL EDTLEQLNAM ITESKRSVRT LKEEVQKLDD LYQQKIKEAE EEDEKCASEL ESLEKHKHLL ESTVNQGLSE AMNELDAVQR EYQLVVQTTT EERRKVGNNL QRLLEMVATH VGSVEKHLEE QIAKVDREYE ECMSEDLSEN IKEIRDKYEK KATLIKSSEE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human HEC1/HEC1/NDC80 (NP_006092.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDC80

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Alternative Name: NDC80

Background: This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.,NDC80,HEC,HEC1,HsHec1,KNTC2,TID3,hsNDC80,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Cell cycle inhibitors,NDC80

Molecular Weight: 73 kDa

Gene ID: 10403

UniProt: O14777

Pathways: Maintenance of Protein Location