HSPB8 antibody

Catalog No. ABIN6144482

This Rabbit Monoclonal antibody specifically detects HSPB8 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for HSPB8 antibody (ABIN6144482)

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HSPB8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-HSPB8 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human HSPB8/HSP22

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000, IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Alternative Name: HSPB8

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22,Neurodegenerative Diseases,Neuroscience,Signal Transduction,HSPB8

Molecular Weight: 22 kDa

Gene ID: 26353

UniProt: Q9UJY1