NEU1 antibody (AA 156-415)

Catalog No. ABIN6144538

This Rabbit Polyclonal antibody specifically detects NEU1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for NEU1 antibody (AA 156-415) (ABIN6144538)

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEU1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NEU1 Antibody

Binding Specificity: AA 156-415

Sequence: SLCAHKAGCQ VASTMLVWSK DDGVSWSTPR NLSLDIGTEV FAPGPGSGIQ KQREPRKGRL IVCGHGTLER DGVFCLLSDD HGASWRYGSG VSGIPYGQPK QENDFNPDEC QPYELPDGSV VINARNQNNY HCHCRIVLRS YDACDTLRPR DVTFDPELVD PVVAAGAVVT SSGIVFFSNP AHPEFRVNLT LRWSFSNGTS WRKETVQLWP GPSGYSSLAT LEGSMDGEEQ APQLYVLYEK GRNHYTESIS VAKISVYGTL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 156-415 of human NEU1 (NP_000425.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NEU1

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Alternative Name: NEU1

Background: The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.,NEU1,NANH,NEU,SIAL1,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,NEU1

Molecular Weight: 45 kDa

Gene ID: 4758

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interactome