NUP50 antibody (AA 299-468)

Catalog No. ABIN6144963

This Rabbit Polyclonal antibody specifically detects NUP50 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for NUP50 antibody (AA 299-468) (ABIN6144963)

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP50 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NUP50 Antibody

Binding Specificity: AA 299-468

Sequence: NSSLFGKDTT QSKPVSSPFP TKPLEGQAEG DSGECKGGDE EENDEPPKVV VTEVKEEDAF YSKKCKLFYK KDNEFKEKGI GTLHLKPTAN QKTQLLVRAD TNLGNILLNV LIPPNMPCTR TGKNNVLIVC VPNPPIDEKN ATMPVTMLIR VKTSEDADEL HKILLEKKDA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 299-468 of human NUP50 (NP_009103.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Alternative Name: NUP50

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.,NUP50,NPAP60,NPAP60L,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,NUP50

Molecular Weight: 46 kDa/50 kDa

Gene ID: 10762

UniProt: Q9UKX7

Pathways: Tube Formation