Occludin antibody (AA 263-522)

Catalog No. ABIN6144996

This anti-Occludin antibody is a Rabbit Polyclonal antibody detecting Occludin in WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Occludin antibody (AA 263-522) (ABIN6144996)

Target: Occludin (OCLN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Occludin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Occludin Antibody

Binding Specificity: AA 263-522

Sequence: FAVKTRRKMD RYDKSNILWD KEHIYDEQPP NVEEWVKNVS AGTQDVPSPP SDYVERVDSP MAYSSNGKVN DKRFYPESSY KSTPVPEVVQ ELPLTSPVDD FRQPRYSSGG NFETPSKRAP AKGRAGRSKR TEQDHYETDY TTGGESCDEL EEDWIREYPP ITSDQQRQLY KRNFDTGLQE YKSLQSELDE INKELSRLDK ELDDYREESE EYMAAADEYN RLKQVKGSAD YKSKKNHCKQ LKSKLSHIKK MVGDYDRQKT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Occludin antibody (ABIN6144996)

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Target Details for Occludin

Target: Occludin (OCLN)

Alternative Name: OCLN

Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.,OCLN,BLCPMG,PPP1R115,PTORCH1,occludin,Occludin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Tight Junctions,Cytoskeleton,OCLN

Molecular Weight: 8 kDa/23 kDa/31 kDa/52 kDa/54 kDa/59 kDa

Gene ID: 100506658

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C