PADI1 antibody (AA 1-260)

Catalog No. ABIN6145161

The Rabbit Polyclonal anti-PADI1 antibody (ABIN6145161) specifically detects PADI1 in WB. The antibody is reactive with Human samples.

Quick Overview for PADI1 antibody (AA 1-260) (ABIN6145161)

Target: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PADI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PADI1 Antibody

Binding Specificity: AA 1-260

Sequence: MAPKRVVQLS LKMPTHAVCV VGVEAHVDIH SDVPKGANSF RVSGSSGVEV FMVYNRTRVK EPIGKARWPL DTDADMVVSV GTASKELKDF KVRVSYFGEQ EDQALGRSVL YLTGVDISLE VDTGRTGKVK RSQGDKKTWR WGPEGYGAIL LVNCDRDNHR SAEPDLTHSW LMSLADLQDM SPMLLSCNGP DKLFDSHKLV LNVPFSDSKR VRVFCARGGN SLSDYKQVLG PQCLSYEVER QPGEQEIKFY VEGLTFPDAD

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PADI1 (NP_037490.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PADI1

Target: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Alternative Name: PADI1

Background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.,PADI1,HPAD10,PAD1,PDI,PDI1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PADI1

Molecular Weight: 74 kDa

Gene ID: 29943

UniProt: Q9ULC6