PCCB antibody (AA 260-539)

Catalog No. ABIN6145281

The Rabbit Polyclonal anti-PCCB antibody has been validated for WB. It is suitable to detect PCCB in samples from Human.

Quick Overview for PCCB antibody (AA 260-539) (ABIN6145281)

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCCB Antibody

Binding Specificity: AA 260-539

Sequence: AFENDVDALC NLRDFFNYLP LSSQDPAPVR ECHDPSDRLV PELDTIVPLE STKAYNMVDI IHSVVDEREF FEIMPNYAKN IIVGFARMNG RTVGIVGNQP KVASGCLDIN SSVKGARFVR FCDAFNIPLI TFVDVPGFLP GTAQEYGGII RHGAKLLYAF AEATVPKVTV ITRKAYGGAY DVMSSKHLCG DTNYAWPTAE IAVMGAKGAV EIIFKGHENV EAAQAEYIEK FANPFPAAVR GFVDDIIQPS STRARICCDL DVLASKKVQR PWRKHANIPL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-539 of human PCCB (NP_000523.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCCB

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Alternative Name: PCCB

Background: The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.,PCCB,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PCCB

Molecular Weight: 58 kDa/60 kDa

Gene ID: 5096

UniProt: P05166

Pathways: Monocarboxylic Acid Catabolic Process