PDE4D antibody (AA 249-518)

Catalog No. ABIN6145355

This anti-PDE4D antibody is a Rabbit Polyclonal antibody detecting PDE4D in WB. Suitable for Human.

Quick Overview for PDE4D antibody (AA 249-518) (ABIN6145355)

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE4D Antibody

Binding Specificity: AA 249-518

Sequence: FKLLQEENCD IFQNLTKKQR QSLRKMVIDI VLATDMSKHM NLLADLKTMV ETKKVTSSGV LLLDNYSDRI QVLQNMVHCA DLSNPTKPLQ LYRQWTDRIM EEFFRQGDRE RERGMEISPM CDKHNASVEK SQVGFIDYIV HPLWETWADL VHPDAQDILD TLEDNREWYQ STIPQSPSPA PDDPEEGRQG QTEKFQFELT LEEDGESDTE KDSGSQVEED TSCSDSKTLC TQDSESTEIP LDEQVEEEAV GEEEESQPEA CVIDDRSPDT

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 249-518 of human PDE4D (NP_001184152.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Alternative Name: PDE4D

Background: This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.,PDE4D,ACRDYS2,DPDE3,HSPDE4D,PDE43,PDE4DN2,STRK1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),PDE4D

Molecular Weight: 23-24 kDa/57-91 kDa

Gene ID: 5144

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling