PGA5 antibody (AA 63-180)
Quick Overview for PGA5 antibody (AA 63-180) (ABIN6145497)
Target
See all PGA5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 63-180
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Sequence
- VDEQPLENYL DMEYFGTIGI GTPAQDFTVV FDTGSSNLWV PSVYCSSLAC TNHNRFNPED SSTYQSTSET VSITYGTGSM TGILGYDTVQ VGGISDTNQI FGLSETEPGS FLYYAPFD
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA5 (NP_055039.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
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Alternative Name
- PGA5
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Background
- This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.,PGA5,Pg5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,PGA5
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Molecular Weight
- 41 kDa
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Gene ID
- 5222
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UniProt
- P0DJD9
Target
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