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PGA5 antibody

PGA5 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 2C1 unconjugated
Catalog No. ABIN969350
  • Target See all PGA5 Antibodies
    PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
    Reactivity
    • 24
    • 1
    • 1
    • 1
    Human
    Host
    • 20
    • 4
    • 1
    Mouse
    Clonality
    • 22
    • 3
    Monoclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PGA5 antibody is un-conjugated
    Application
    • 18
    • 12
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human PGA5 expressed in E. coli.
    Clone
    2C1
    Isotype
    IgG1
    Top Product
    Discover our top product PGA5 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
    Alternative Name
    PGA5 (PGA5 Products)
    Synonyms
    PGA3 antibody, PGA4 antibody, 1110035E17Rik antibody, Pepf antibody, pepsinogen 5, group I (pepsinogen A) antibody, pepsinogen 5, group I antibody, PGA5 antibody, Pga5 antibody
    Background

    Description: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

    Aliases: Pepsinogen 5, Pepsin A

    Molecular Weight
    42 kDa
    Gene ID
    5222
    HGNC
    5222
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