PHOX2B antibody (AA 1-90)

Catalog No. ABIN6145577

This anti-PHOX2B antibody is a Rabbit Polyclonal antibody detecting PHOX2B in WB. Suitable for Human.

Quick Overview for PHOX2B antibody (AA 1-90) (ABIN6145577)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHOX2B Antibody

Binding Specificity: AA 1-90

Sequence: MYKMEYSYLN SSAYESCMAG MDTSSLASAY ADFSSCSQAS GFQYNPIRTT FGATSGCPSL TPGSCSLGTL RDHQSSPYAA VPYKLFTDHG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PHOX2B (NP_003915.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.,PHOX2B,NBLST2,NBPhox,PMX2B,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Neuroscience,PHOX2B

Molecular Weight: 31 kDa

Gene ID: 8929

UniProt: Q99453