PIAS3 antibody (AA 399-628)

Catalog No. ABIN6145598

This Rabbit Polyclonal antibody specifically detects PIAS3 in IF. It exhibits reactivity toward Human.

Quick Overview for PIAS3 antibody (AA 399-628) (ABIN6145598)

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIAS3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-PIAS3 Antibody

Binding Specificity: AA 399-628

Sequence: FMEDGSWCPM KPKKEASEVC PPPGYGLDGL QYSPVQGGDP SENKKKVEVI DLTIESSSDE EDLPPTKKHC SVTSAAIPAL PGSKGVLTSG HQPSSVLRSP AMGTLGGDFL SSLPLHEYPP AFPLGADIQG LDLFSFLQTE SQHYGPSVIT SLDEQDALGH FFQYRGTPSH FLGPLAPTLG SSHCSATPAP PPGRVSSIVA PGGALREGHG GPLPSGPSLT GCRSDIISLD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 399-628 of human PIAS3 (NP_006090.2).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIAS3

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Alternative Name: PIAS3

Background: This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.,PIAS3,ZMIZ5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PIAS3

Molecular Weight: 68 kDa

Gene ID: 10401

UniProt: Q9Y6X2

Pathways: JAK-STAT Signaling