Plakophilin 2 antibody (AA 578-837)

Catalog No. ABIN6145717

The Rabbit Polyclonal anti-Plakophilin 2 antibody has been validated for WB. It is suitable to detect Plakophilin 2 in samples from Human.

Quick Overview for Plakophilin 2 antibody (AA 578-837) (ABIN6145717)

Target: Plakophilin 2 (PKP2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Plakophilin 2 Antibody

Binding Specificity: AA 578-837

Sequence: LPEKYSQNIY IQNRNIQTDN NKSIGCFGSR SRKVKEQYQD VPMPEEKSNP KGVEWLWHSI VIRMYLSLIA KSVRNYTQEA SLGALQNLTA GSGPMPTSVA QTVVQKESGL QHTRKMLHVG DPSVKKTAIS LLRNLSRNLS LQNEIAKETL PDLVSIIPDT VPSTDLLIET TASACYTLNN IIQNSYQNAR DLLNTGGIQK IMAISAGDAY ASNKASKAAS VLLYSLWAHT ELHHAYKKAQ FKKTDFVNSR TAKAYHSLKD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 578-837 of human PKP2 (NP_001005242.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Plakophilin 2

Target: Plakophilin 2 (PKP2)

Alternative Name: PKP2

Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.,PKP2,ARVD9,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Neuroscience,Cardiovascular,Angiogenesis,PKP2

Molecular Weight: 92 kDa/97 kDa

Gene ID: 5318

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection