POLR1B antibody (AA 670-900)

Catalog No. ABIN6145908

The Rabbit Polyclonal anti-POLR1B antibody has been validated for WB. It is suitable to detect POLR1B in samples from Human.

Quick Overview for POLR1B antibody (AA 670-900) (ABIN6145908)

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLR1B Antibody

Binding Specificity: AA 670-900

Sequence: IANFIPFSDH NQSPRNMYQC QMGKQTMGFP LLTYQDRSDN KLYRLQTPQS PLVRPSMYDY YDMDNYPIGT NAIVAVISYT GYDMEDAMIV NKASWERGFA HGSVYKSEFI DLSEKIKQGD SSLVFGIKPG DPRVLQKLDD DGLPFIGAKL QYGDPYYSYL NLNTGESFVM YYKSKENCVV DNIKVCSNDT GSGKFKCVCI TMRVPRNPTI GDKFASRHGQ KGILSRLWPA E

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 670-900 of human POLR1B (NP_061887.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POLR1B

Target: POLR1B (Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))

Alternative Name: POLR1B

Background: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008],POLR1B,RPA135,RPA2,Rpo1-2,Epigenetics & Nuclear Signaling,POLR1B

Molecular Weight: 104 kDa/107 kDa/121 kDa/128 kDa/132 kDa

Gene ID: 84172

UniProt: Q9H9Y6