Hemoglobin Subunit beta antibody (AA 38-148)

Catalog No. ABIN614613

The Mouse Monoclonal anti-Hemoglobin Subunit beta antibody (Clone 7B12) (ABIN614613) specifically detects Hemoglobin Subunit beta in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for Hemoglobin Subunit beta antibody (AA 38-148) (ABIN614613)

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hemoglobin Subunit beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 7B12

Product Details anti-Hemoglobin Subunit beta Antibody

Binding Specificity: AA 38-148

Specificity: This antibody recognizes Hemoglobin Beta (HBB).

Purification: Protein A Chromatography

Immunogen: Recombinant protein, HBB (AAH07075, 38 a.a. ~ 148 a.a) partial recombinant protein with GST tag. Genename: HBB

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Hemoglobin Subunit beta

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Alternative Name: Hemoglobin beta Chain

Background: The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin that sickles causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.Synonyms: Beta-globin, HBB

Gene ID: 3043

NCBI Accession: NP_000509

UniProt: P68871