PRDM2 antibody (AA 50-150)

Catalog No. ABIN6146141

This Rabbit Polyclonal antibody specifically detects PRDM2 in WB. It exhibits reactivity toward Human.

Quick Overview for PRDM2 antibody (AA 50-150) (ABIN6146141)

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRDM2 Antibody

Binding Specificity: AA 50-150

Sequence: ILKGKKFGPF VGDKKKRSQV KNNVYMWEVY YPNLGWMCID ATDPEKGNWL RYVNWACSGE EQNLFPLEIN RAIYYKTLKP IAPGEELLVW YNGEDNPEIA A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PRDM2 (NP_036363.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRDM2

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Alternative Name: PRDM2

Background: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.,PRDM2,HUMHOXY1,KMT8,KMT8A,MTB-ZF,RIZ,RIZ1,RIZ2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Neuroscience,PRDM2

Molecular Weight: 25 kDa/162 kDa/166 kDa/184 kDa/188 kDa

Gene ID: 7799

UniProt: Q13029