Peroxiredoxin 1 antibody (AA 1-199)

Catalog No. ABIN6146151

The Rabbit Polyclonal anti-Peroxiredoxin 1 antibody has been validated for WB. It is suitable to detect Peroxiredoxin 1 in samples from Human.

Quick Overview for Peroxiredoxin 1 antibody (AA 1-199) (ABIN6146151)

Target: Peroxiredoxin 1 (PRDX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Peroxiredoxin 1 Antibody

Binding Specificity: AA 1-199

Sequence: MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human Peroxiredoxin 1/PAG (NP_001189360.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: PRDX1

Background: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.,PRDX1,MSP23,NKEF-A,NKEFA,PAG,PAGA,PAGB,PRX1,PRXI,TDPX2,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Endocrine & Metabolism,Immunology & Inflammation,Cardiovascular,PRDX1

Molecular Weight: 22 kDa

Gene ID: 5052

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events