PRIM2 antibody (AA 1-170)

Catalog No. ABIN6146164

The Rabbit Polyclonal anti-PRIM2 antibody has been validated for WB. It is suitable to detect PRIM2 in samples from Human.

Quick Overview for PRIM2 antibody (AA 1-170) (ABIN6146164)

Target: PRIM2 (Primase, DNA, Polypeptide 2 (58kDa) (PRIM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRIM2 Antibody

Binding Specificity: AA 1-170

Sequence: MEFSGRKWRK LRLAGDQRNA SYPHCLQFYL QPPSENISLI EFENLAIDRV KLLKSVENLG VSYVKGTEQY QSKLESELRK LKFSYRENLE DEYEPRRRDH ISHFILRLAY CQSEELRRWF IQQEMDLLRF RFSILPKDKI QDFLKDSQLQ FEAISDEEKT LREQEIVASS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human PRIM2 (NP_000938.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRIM2

Target: PRIM2 (Primase, DNA, Polypeptide 2 (58kDa) (PRIM2))

Alternative Name: PRIM2

Background: This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6.,PRIM2,PRIM2A,p58,Epigenetics & Nuclear Signaling,PRIM2

Molecular Weight: 19 kDa/58 kDa

Gene ID: 5558

UniProt: P49643

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, SARS-CoV-2 Protein Interactome