PSMD9 antibody (AA 1-223)

Catalog No. ABIN6146349

The Rabbit Polyclonal anti-PSMD9 antibody (ABIN6146349) specifically detects PSMD9 in WB. The antibody is reactive with Human samples.

Quick Overview for PSMD9 antibody (AA 1-223) (ABIN6146349)

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD9 Antibody

Binding Specificity: AA 1-223

Sequence: MSDEEARQSG GSSQAGVVTV SDVQELMRRK EEIEAQIKAN YDVLESQKGI GMNEPLVDCE GYPRSDVDLY QVRTARHNII CLQNDHKAVM KQVEEALHQL HARDKEKQAR DMAEAHKEAM SRKLGQSESQ GPPRAFAKVN SISPGSPASI AGLQVDDEIV EFGSVNTQNF QSLHNIGSVV QHSEGKPLNV TVIRRGEKHQ LRLVPTRWAG KGLLGCNIIP LQR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human PSMD9 (NP_002804.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMD9

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Alternative Name: PSMD9

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.,PSMD9,Rpn4,p27,Cell Biology & Developmental Biology,Ubiquitin,PSMD9

Molecular Weight: 13 kDa/22 kDa/24 kDa

Gene ID: 5715

UniProt: O00233

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway