PUS1 antibody (AA 308-427)

Catalog No. ABIN6146504

This anti-PUS1 antibody is a Rabbit Polyclonal antibody detecting PUS1 in WB. Suitable for Human.

Quick Overview for PUS1 antibody (AA 308-427) (ABIN6146504)

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PUS1 Antibody

Binding Specificity: AA 308-427

Sequence: YAPESVLERS WGTEKVDVPK APGLGLVLER VHFEKYNQRF GNDGLHEPLD WAQEEGKVAA FKEEHIYPTI IGTERDERSM AQWLSTLPIH NFSATALTAG GTGAKVPSPL EGSEGDGDTD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 308-427 of human PUS1 (NP_079491.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PUS1

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Alternative Name: PUS1

Background: This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.,PUS1,MLASA1,Epigenetics & Nuclear Signaling,RNA Binding,PUS1

Molecular Weight: 44 kDa/47 kDa

Gene ID: 80324

UniProt: Q9Y606