RASGRP3 antibody (AA 540-689)
Quick Overview for RASGRP3 antibody (AA 540-689) (ABIN6146722)
Target
See all RASGRP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 540-689
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Sequence
- VLACRRFARA PSLSSGHGSL PGSPSLPPAQ DEVFEFPGVT AGHRDLDSRA ITLVTGSSRK ISVRLQRATT SQATQTEPVW SEAGWGDSGS HTFPKMKSKF HDKAAKDKGF AKWENEKPRV HAGVDVVDRG TEFELDQDEG EETRQDGEDG
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 540-689 of human RASGRP3 (NP_056191.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))
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Alternative Name
- RASGRP3
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Background
- The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.,RASGRP3,GRP3,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,RASGRP3
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Molecular Weight
- 78 kDa
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Gene ID
- 25780
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UniProt
- Q8IV61
Target
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