RCAN1 antibody (AA 60-245)

Catalog No. ABIN6146811

This anti-RCAN1 antibody is a Rabbit Polyclonal antibody detecting RCAN1 in WB and IHC. Suitable for Human.

Quick Overview for RCAN1 antibody (AA 60-245) (ABIN6146811)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RCAN1 Antibody

Binding Specificity: AA 60-245

Sequence: DLQDLPSATI ACHLDPRVFV DGLCRAKFES LFRTYDKDIT FQYFKSFKRV RINFSNPFSA ADARLQLHKT EFLGKEMKLY FAQTLHIGSS HLAPPNPDKQ FLISPPASPP VGWKQVEDAT PVINYDLLYA ISKLGPGEKY ELHAATDTTP SVVVHVCESD QEKEEEEEME RMRRPKPKII QTRRPE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1 (NP_004405.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Alternative Name: RCAN1

Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.,RCAN1,ADAPT78,CSP1,DSC1,DSCR1,MCIP1,RCN1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,RCAN1

Molecular Weight: 13 kDa/19 kDa/22 kDa/28 kDa

Gene ID: 1827

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development