REV1 antibody (AA 120-345)

Catalog No. ABIN6146877

This Rabbit Polyclonal antibody specifically detects REV1 in WB. It exhibits reactivity toward Human.

Quick Overview for REV1 antibody (AA 120-345) (ABIN6146877)

Target: REV1 (REV1, Polymerase (DNA Directed) (REV1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REV1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-REV1 Antibody

Binding Specificity: AA 120-345

Sequence: AGRLLSYIPY QLYTKQSSVQ KGLSFNPVCR PEDPLPGPSN IAKQLNNRVN HIVKKIETEN EVKVNGMNSW NEEDENNDFS FVDLEQTSPG RKQNGIPHPR GSTAIFNGHT PSSNGALKTQ DCLVPMVNSV ASRLSPAFSQ EEDKAEKSST DFRDCTLQQL QQSTRNTDAL RNPHRTNSFS LSPLHSNTKI NGAHHSTVQG PSSTKSTSSV STFSKAAPSV PSKPSD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-345 of human REV1 (NP_057400.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for REV1

Target: REV1 (REV1, Polymerase (DNA Directed) (REV1))

Alternative Name: REV1

Background: This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.,REV1,AIBP80,REV1L,Epigenetics & Nuclear Signaling,DNA Damage & Repair,REV1

Molecular Weight: 43 kDa/138 kDa

Gene ID: 51455

UniProt: Q9UBZ9

Pathways: DNA Damage Repair, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response