RGR antibody (AA 156-295)

Catalog No. ABIN6146910

The Rabbit Polyclonal anti-RGR antibody has been validated for WB. It is suitable to detect RGR in samples from Human.

Quick Overview for RGR antibody (AA 156-295) (ABIN6146910)

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGR Antibody

Binding Specificity: AA 156-295

Sequence: HYDYEPLGTC CTLDYSKGDR NFTSFLFTMS FFNFAMPLFI TITSYSLMEQ KLGKSGHLQV NTTLPARTLL LGWGPYAILY LYAVIADVTS ISPKLQMVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 156-295 of human RGR (NP_002912.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Alternative Name: RGR

Background: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.,RGR,RP44,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,RGR

Molecular Weight: 27 kDa/31 kDa/32 kDa

Gene ID: 5995

UniProt: P47804