RGS5 antibody (AA 1-181)

Catalog No. ABIN6146924

The Rabbit Polyclonal anti-RGS5 antibody (ABIN6146924) specifically detects RGS5 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for RGS5 antibody (AA 1-181) (ABIN6146924)

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RGS5 Antibody

Binding Specificity: AA 1-181

Sequence: MCKGLAALPH SCLERAKEIK IKLGILLQKP DSVGDLVIPY NEKPEKPAKT QKTSLDEALQ WRDSLDKLLQ NNYGLASFKS FLKSEFSEEN LEFWIACEDY KKIKSPAKMA EKAKQIYEEF IQTEAPKEVN IDHFTKDITM KNLVEPSLSS FDMAQKRIHA LMEKDSLPRF VRSEFYQELI K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS5 (NP_003608.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS5

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Alternative Name: RGS5

Background: This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.,RGS5,MST092,MST106,MST129,MSTP032,MSTP092,MSTP106,MSTP129,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,Cardiovascular,Angiogenesis,Blood,Blood Pressure regulation,Heart,Hypertrophy,RGS5

Molecular Weight: 8 kDa/20 kDa/21 kDa

Gene ID: 8490

UniProt: O15539

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling