RIN1 antibody (AA 1-280)

Catalog No. ABIN6146951

The Rabbit Polyclonal anti-RIN1 antibody has been validated for WB. It is suitable to detect RIN1 in samples from Human.

Quick Overview for RIN1 antibody (AA 1-280) (ABIN6146951)

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIN1 Antibody

Binding Specificity: AA 1-280

Sequence: MESPGESGAG SPGAPSPSSF TTGHLAREKP AQDPLYDVPN ASGGQAGGPQ RPGRVVSLRE RLLLTRPVWL QLQANAAAAL HMLRTEPPGT FLVRKSNTRQ CQALCMRLPE ASGPSFVSSH YILESPGGVS LEGSELMFPD LVQLICAYCH TRDILLLPLQ LPRAIHHAAT HKELEAISHL GIEFWSSSLN IKAQRGPAGG PVLPQLKARS PQELDQGTGA ALCFFNPLFP GDLGPTKREK FKRSFKVRVS TETSSPLSPP AVPPPPVPVL PGAVPSQTER

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RIN1 (NP_004283.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Alternative Name: RIN1

Background: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.,RIN1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Neuroscience,RIN1

Molecular Weight: 77 kDa/84 kDa

Gene ID: 9610

UniProt: Q13671