RIN1 antibody (AA 20-70)

Catalog No. ABIN6242616

The Rabbit Polyclonal anti-RIN1 antibody is suitable to detect RIN1 in samples from Human. It has been validated for WB.

Quick Overview for RIN1 antibody (AA 20-70) (ABIN6242616)

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB46939

Product Details anti-RIN1 Antibody

Binding Specificity: AA 20-70

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-70 amino acids from human.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Alternative Name: RIN1

Background: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Molecular Weight: 84099

UniProt: Q13671