RNGTT antibody (AA 1-260)

Catalog No. ABIN6147053

This anti-RNGTT antibody is a Rabbit Polyclonal antibody detecting RNGTT in WB and IF. Suitable for Human.

Quick Overview for RNGTT antibody (AA 1-260) (ABIN6147053)

Target: RNGTT (RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNGTT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RNGTT Antibody

Binding Specificity: AA 1-260

Sequence: MAHNKIPPRW LNCPRRGQPV AGRFLPLKTM LGPRYDSQVA EENRFHPSML SNYLKSLKVK MGLLVDLTNT SRFYDRNDIE KEGIKYIKLQ CKGHGECPTT ENTETFIRLC ERFNERNPPE LIGVHCTHGF NRTGFLICAF LVEKMDWSIE AAVATFAQAR PPGIYKGDYL KELFRRYGDI EEAPPPPLLP DWCFEDDEDE DEDEDGKKES EPGSSASFGK RRKERLKLGA IFLEGVTVKG VTQVTTQPKL GEVQQKCHQF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNGTT (NP_003791.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNGTT

Target: RNGTT (RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))

Alternative Name: RNGTT

Background: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.,RNGTT,CAP1A,HCE,HCE1,hCAP,Epigenetics & Nuclear Signaling,RNGTT

Molecular Weight: 52 kDa/61 kDa/66 kDa/68 kDa

Gene ID: 8732

UniProt: O60942