RORA antibody (AA 169-468)

Catalog No. ABIN6147077

This Rabbit Polyclonal antibody specifically detects RORA in WB. It exhibits reactivity toward Human.

Quick Overview for RORA antibody (AA 169-468) (ABIN6147077)

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RORA Antibody

Binding Specificity: AA 169-468

Sequence: DIQPSPDQSG LDINGIKPEP ICDYTPASGF FPYCSFTNGE TSPTVSMAEL EHLAQNISKS HLETCQYLRE ELQQITWQTF LQEEIENYQN KQREVMWQLC AIKITEAIQY VVEFAKRIDG FMELCQNDQI VLLKAGSLEV VFIRMCRAFD SQNNTVYFDG KYASPDVFKS LGCEDFISFV FEFGKSLCSM HLTEDEIALF SAFVLMSADR SWLQEKVKIE KLQQKIQLAL QHVLQKNHRE DGILTKLICK VSTLRALCGR HTEKLMAFKA IYPDIVRLHF PPLYKELFTS EFEPAMQIDG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 169-468 of human RORA (NP_599024.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RORA

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Alternative Name: RORA

Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.,RORA,NR1F1,ROR1,ROR2,ROR3,RZR-ALPHA,RZRA,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Neuroscience,RORA

Molecular Weight: 53 kDa/58 kDa/61 kDa/63 kDa

Gene ID: 6095

UniProt: P35398

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha