SECISBP2 antibody (AA 585-854)

Catalog No. ABIN6147497

This anti-SECISBP2 antibody is a Rabbit Polyclonal antibody detecting SECISBP2 in WB, IF and IHC. Suitable for Human.

Quick Overview for SECISBP2 antibody (AA 585-854) (ABIN6147497)

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SECISBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-SECISBP2 Antibody

Binding Specificity: AA 585-854

Sequence: DELISTPSVE DKSEEPPGTE LQRDTEASHL APNHTTFPKI HSRRFRDYCS QMLSKEVDAC VTDLLKELVR FQDRMYQKDP VKAKTKRRLV LGLREVLKHL KLKKLKCVII SPNCEKIQSK GGLDDTLHTI IDYACEQNIP FVFALNRKAL GRSLNKAVPV SVVGIFSYDG AQDQFHKMVE LTVAARQAYK TMLENVQQEL VGEPRPQAPP SLPTQGPSCP AEDGPPALKE KEEPHYIEIW KKHLEAYSGC TLELEESLEA STSQMMNLNL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 585-854 of human SECISBP2 (NP_076982.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SECISBP2

Target: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Alternative Name: SECISBP2

Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.,SECISBP2,SBP2,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Amino acid metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,SECISBP2

Molecular Weight: 87 kDa/95 kDa

Gene ID: 79048

UniProt: Q96T21