alpha 2 Antiplasmin antibody (AA 302-491)

Catalog No. ABIN6147609

The Rabbit Polyclonal anti-alpha 2 Antiplasmin antibody has been validated for WB, IHC and IF. It is suitable to detect alpha 2 Antiplasmin in samples from Human.

Quick Overview for alpha 2 Antiplasmin antibody (AA 302-491) (ABIN6147609)

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-alpha 2 Antiplasmin Antibody

Binding Specificity: AA 302-491

Sequence: VPTHFEWNVS QVLANLSWDT LHPPLVWERP TKVRLPKLYL KHQMDLVATL SQLGLQELFQ APDLRGISEQ SLVVSGVQHQ STLELSEVGV EAAAATSIAM SRMSLSSFSV NRPFLFFIFE DTTGLPLFVG SVRNPNPSAP RELKEQQDSP GNKDFLQSLK GFPRGDKLFG PDLKLVPPME EDYPQFGSPK

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 302-491 of human SERPINF2 (NP_001159392.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: SERPINF2

Background: This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.,SERPINF2,A2AP,AAP,ALPHA-2-PI,API,PLI,Cell Biology & Developmental Biology,Ubiquitin,Cardiovascular,Blood,Coagulation,SERPINF2

Molecular Weight: 47 kDa/54 kDa

Gene ID: 5345

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones