SESN3 antibody (AA 1-310)

Catalog No. ABIN6147627

This anti-SESN3 antibody is a Rabbit Polyclonal antibody detecting SESN3 in WB. Suitable for Human.

Quick Overview for SESN3 antibody (AA 1-310) (ABIN6147627)

Target: SESN3 (Sestrin 3 (SESN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SESN3 Antibody

Binding Specificity: AA 1-310

Sequence: MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SESN3

Target: SESN3 (Sestrin 3 (SESN3))

Alternative Name: SESN3

Background: This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.,SESN3,SEST3,sestrin-3,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Hypoxia,Hypoxia-Regulated,SESN3

Molecular Weight: 36 kDa/41 kDa/57 kDa

Gene ID: 143686

UniProt: P58005